A 2010 graduate of Northwest High School Preston competed in football and basketball. As a senior basketball player, his team earned a share of the league championship and Preston was named 1st Team All-FAVC. He is a three-year varsity letter winner in football, a two-time 1st Team All-FAVC, 1st Team All-City selection, 1st Team All-District and 2nd Team All-State honors recipient. While at Northwest he played linebacker and running back – rushing for 1,000 all-purpose yards and 15 touchdowns as a senior. He was an active member of the U-Knighted Knights. In recognition of his outstanding service and achievements, Preston was voted into the NWHS Hall of Fame Class of 2015.

From NW, Preston earned a full athletic scholarship to the University of Louisville and graduated early, in December 2013, with a bachelor’s degree in education. Playing for Coach Charlie Strong, he was a three-year starter at linebacker amassing a career total of 301 tackles. During his junior season, Preston emerged as one of the leading linebackers in the country for a Louisville team that went 11-2, won a Big East Championship, and beat Florida in the Sugar Bowl.  While at Louisville he earned 2nd Team All-Big East and 2nd Team All-American Athletic Conference selections. As a senior, he led Louisville in tackles as the Cardinals went 12-1 and won the American Athletic Conference. Preston was named to the Kentucky Pro Football Hall of Fame All-Collegiate Team and selected to play in the East-West Shrine All-Star Game.

In the 2014 NFL Draft Preston was selected by the Buffalo Bills in the 3rd round (73rd overall pick). As a rookie linebacker, he recorded 109 tackles - the most among Bills’ defenders and second among NFL rookies. He produced 100+ tackles in each of his first four NFL seasons. During the 2017 season, Preston led the NFL with 144 tackles. In 2018, as an Unrestricted Free Agent, Preston signed to play for his hometown Cincinnati Bengals, where he played the better part of two seasons before becoming a free agent and later retiring as a 6-year NFL vet. The Preston Brown Family Foundation, which he founded in 2017, proudly supports NWHS with initiatives that support optimal well-being. Preston focuses on giving back to the community through a variety of outlets, including an annual free Youth Football Camp.